PulmonologyNews.net

Pulmonology Xagena

Many patients with severe asthma require regular treatment with oral glucocorticoids despite the use of high-dose inhaled therapy. However, the regular use of systemic glucocorticoids can result in se ...


Pulmonary vascular leakage occurs early in acute respiratory distress syndrome ( ARDS ). Mortality is high ( 35–45% ), but no effective pharmacotherapy exists. Production of anti-inflammatory adenosin ...


Pirfenidone ( Esbriet ) is a novel antifibrotic drug for the treatment of mild-to-moderate idiopathic pulmonary fibrosis ( IPF ). However, adverse events may offset treatment benefits and compliance. ...


Aclidinium bromide / Formoterol fumarate ( 400/12 mcg ) is a fixed dose combination of two approved long-acting bronchodilators with different mechanisms of action and similar pharmocodynamic profiles ...


Increased arterial stiffness as measured by aortic pulse wave velocity ( aPWV ) predicts cardiovascular events and mortality and is elevated in patients with COPD ( chronic obstructive pulmonary disea ...


Arformoterol tartrate ( Arformoterol, 15 mcg bid; Brovana ) is a nebulized long-acting β2-agonist approved for maintenance treatment of COPD ( chronic obstructive pulmonary disease ). This was a mu ...


Lung injury is a serious complication of surgery. A systematic review and meta-analysis were done to assess whether incidence, morbidity, and in-hospital mortality associated with postoperative lung i ...


Long-term macrolide treatment has proven benefit in inflammatory airways diseases, but whether it leads to changes in the composition of respiratory microbiota is unknown. A study aimed to assess wh ...


Bronchial thermoplasty is a procedure that consists of the delivery of controlled radiofrequency-generated heat via a catheter inserted into the bronchial tree of the lungs through a flexible bronchos ...


The FDA ( Food and Drug Administration ) has approved Ofev ( Nintedanib ) for the treatment of idiopathic pulmonary fibrosis ( IPF ), a debilitating and fatal lung disease, which has a median survival ...


Results from a third lung function study comparing the efficacy and safety of Umeclidinium and Vilanterol ( Anoro Ellipta; UMEC/VI ), a combination long-acting muscarinic antagonist ( LAMA ) / long-ac ...


Results published in the New England Journal of Medicine ( NEJM ) and presented at the European Respiratory Society ( ERS ) congress provide further data from the two pivotal Phase III asthma studies ...


A pre-specified subgroup analysis from the two replicate Phase III INPULSIS trials, presented at the European Respiratory Society International Congress ( ERS ), has shown Nintedanib slowed disease pr ...


Omalizumab ( Xolair ) has been recommended as an add-on option for the treatment of patients with moderate-severe allergic asthma uncontrolled with high doses of corticoid inhaled therapy. In addition ...


Once-daily Tiotropium ( Spiriva ) Respimat, a long-acting anticholinergic bronchodilator, has been shown in a phase III program to improve lung function and reduce severe exacerbation risk in severe a ...