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In a study with mice, researchers at Johns Hopkins Bloomberg School of Public Health have found that e-cigarettes compromise the immune system in the lungs and generate some of the same potentially da ...


Key goals in the treatment of community-acquired pneumonia ( CAP ) include early response to treatment and achievement of clinical stability. The US FDA ( Food and Drug Admnistration ) recommends ea ...


Although high-dose N-Acetylcysteine ( NAC; Acetylcysteine; Fluimucil ) has been suggested to reduce COPD ( chronic obstructive pulmonary disease ) exacerbations, it is unclear which category of patien ...


Ambrisentan ( US: Letairis; EU: Volibris ) is an oral selective endothelin receptor antagonist licensed for use in pulmonary arterial hypertension ( PAH ). There are few data on clinical use and lon ...


Riociguat ( Adempas ) is a soluble guanylate cyclase stimulator approved for the treatment of inoperable and persistent / recurrent chronic thromboembolic pulmonary hypertension ( CTEPH ). In the ...


Researchers have conducted a meta-analysis of randomised trials to evaluate the efficacy and safety of inhaled antibiotics in patients with stable non-cystic fibrosis ( CF ) bronchiectasis. 12 tria ...


Many patients with severe asthma require regular treatment with oral glucocorticoids despite the use of high-dose inhaled therapy. However, the regular use of systemic glucocorticoids can result in se ...


Pulmonary vascular leakage occurs early in acute respiratory distress syndrome ( ARDS ). Mortality is high ( 35–45% ), but no effective pharmacotherapy exists. Production of anti-inflammatory adenosin ...


Pirfenidone ( Esbriet ) is a novel antifibrotic drug for the treatment of mild-to-moderate idiopathic pulmonary fibrosis ( IPF ). However, adverse events may offset treatment benefits and compliance. ...


Aclidinium bromide / Formoterol fumarate ( 400/12 mcg ) is a fixed dose combination of two approved long-acting bronchodilators with different mechanisms of action and similar pharmocodynamic profiles ...


Increased arterial stiffness as measured by aortic pulse wave velocity ( aPWV ) predicts cardiovascular events and mortality and is elevated in patients with COPD ( chronic obstructive pulmonary disea ...


Arformoterol tartrate ( Arformoterol, 15 mcg bid; Brovana ) is a nebulized long-acting β2-agonist approved for maintenance treatment of COPD ( chronic obstructive pulmonary disease ). This was a mu ...


Lung injury is a serious complication of surgery. A systematic review and meta-analysis were done to assess whether incidence, morbidity, and in-hospital mortality associated with postoperative lung i ...


Long-term macrolide treatment has proven benefit in inflammatory airways diseases, but whether it leads to changes in the composition of respiratory microbiota is unknown. A study aimed to assess wh ...


Bronchial thermoplasty is a procedure that consists of the delivery of controlled radiofrequency-generated heat via a catheter inserted into the bronchial tree of the lungs through a flexible bronchos ...