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Search results for "Bronchiectasis"

Mannose-binding lectin ( MBL ) is a key component of innate immunity. MBL deficiency is common ( 10-30% of the general population depending on the definition used ) and has been associated with diseas ...


Bronchiectasis develops early in the course of cystic fibrosis, being detectable in infants as young as 10 weeks of age, and is persistent and progressive. Researchers have determined risk factors for ...


Mucus plugging and hypersecretion have been associated with an increased relative risk of death in patients with bronchiectasis who may or may not have chronic obstructive pulmonary disease ( COPD ), ...


Long-term macrolide treatment has proven benefit in inflammatory airways diseases, but whether it leads to changes in the composition of respiratory microbiota is unknown. A study aimed to assess wh ...


Researchers have conducted a meta-analysis of randomised trials to evaluate the efficacy and safety of inhaled antibiotics in patients with stable non-cystic fibrosis ( CF ) bronchiectasis. 12 tria ...


Haemoptysis is a serious symptom with various aetiologies. The aim of a study was to define the aetiologies, outcomes and associations with lung cancer in the entire population of a high-income countr ...


No prospective study has assessed eradication treatment of early Pseudomonas aeruginosa ( P. aeruginosa ) colonisation in bronchiectasis not due to cystic fibrosis. Researchers have evaluated the e ...


This randomised double-blind placebo-controlled parallel-group multicentre phase IIa study evaluated the effect of the CXCR2 antagonist AZD5069 on sputum neutrophil counts in adults with bronchiectasi ...


Eradication and suppression of Pseudomonas aeruginosa ( P. aeruginosa ) is a key priority in national guidelines for bronchiectasis, and is a major focus of drug development and clinical trials. An ac ...